Description
Poloxamer 407. also known as Pluronic F127. is a Triblock copolymer composed of polyoxyethylene and polypropylene. This versatile Non-ionic surfactant is known for its excellent solubilizing, emulsifying, and stabilizing properties. Poloxamer 407 is widely used in Pharmaceuticals, personal care products, and industrial applications due to its unique characteristics and high safety profile.
Application
Pharmaceuticals: Poloxamer 407 is used in pharmaceutical formulations as a solubilizer, emulsifier, and stabilizer. It is particularly useful in controlled-release drug delivery systems, topical gels, and injectable formulations.
Personal Care Products: It is widely used in personal care products, including shampoos, conditioners, body washes, and lotions. Poloxamer 407 enhances the texture, stability, and performance of these products.
Cosmetics: In Cosmetics, Poloxamer 407 is used to create smooth and stable formulations. It helps in the emulsification of creams and lotions and enhances the sensory properties of makeup products.
Ophthalmic Solutions: Poloxamer 407 is used in eye drops and other ophthalmic solutions for its non-irritating properties and ability to form clear, stable solutions.
Industrial Applications: It is utilized in industrial applications such as detergents, cleaning agents, and coatings for its emulsifying and stabilizing properties.
Biomedical Applications: Poloxamer 407 is employed in biomedical applications, including tissue engineering, wound care products, and as a component in hydrogel-based drug delivery systems.
Specifications
| Items | Specification | Results |
| Identification (IR) | Matches standard scan | Pass |
| Appearance of solution | Less than BY17 | Pass |
| Clarity and color of solution | Clear and colorless | pass |
| Acid | Red solution | pass |
| Ph value(25g/L in water) | 5.0-7.5 | 6.5 |
| Ph value(100g/L in water) | 5.0-7.5 | 6.7 |
| Average molecular weight | 9840g/mol~14600g/mol | 13339g/mol |
| Oxyethylene | 71.5%~74.9% | 72.2% |
| Total ash | ≤0.4% | 0.2% |
| Residue on ignition | ≤0.30% | 0.27% |
| Unsaturation | 0.031mEq/G~0.065mEq/G | 0.051mEq/G |
| Water | ≤0.75% | 0.05% |
| Heavy metals | <0.002% | Pass |
| BHT stabilizer | 50ppm~125ppm | 103ppm |
| Congealing point | 50°C~62°C | 52°C |
| APHA Color(50:50 in MeOH) | ≤120 | 50 |
| Cloud point, 10% solution | ≥100°C | >100°C |
| Residual solvent | Meets USP requirements | Pass |
| Sun ethylene and diethylene glycol | <0.25wt% | Pass |
| 1.4 dioxane | ≤5.0ppm | 0.1ppm |
| Ethylene oxide | ≤1.0ppm | 0.1ppm |
| Propylene oxide | ≤5.0ppm | 0.9ppm |
| Arsenic | <2ppm | Pass |
Type of Packaging:
90KG/cardboard barrel
Certifications
ISO 9001. ISO 22716. cGMP certified
Kosher, Halal certified
Shipping Information
MOQ: (Due to the nature of chemical transportation, please consult the sea trade manager for details!)
Port of Loading: CHINA - Shanghai Port, Ningbo Zhoushan Port, Guangzhou Port, Qingdao Port, Tianjin Port, Dalian Port, Xiamen Port, Lianyungang Port (can be ensured according to the requirements of customers)
Delivery Time: 4-6 weeks, depending on order size and destination
Payment Terms
L/C, D/P, T/T at buyer’s cost
Sample available on request
Multiple Names
Polyether polyol
Polyoxyethylene-polyoxypropylene Block Copolymer
Poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
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