Description
colorless transparent liquid, with odor of ester. Boiling point 103 -105 °C, Relative Density 0.9676(20/4 °C), Refractive index 1.3773 (2.5 °C), Flash point 15 °C, soluble in ethanol and ether and decomposable in water.
Application
Trimethyl orthoformate is a useful building block for creating methoxymethylene groups and heterocyclic ring systems. It introduces a formyl group to a nucleophilic substrate, e.g. RNH2 to form R-NH-CHO, which can undergo further reactions. It is used in the production of some fungicides (for example: azoxystrobin and picoxystrobin), as well as for some members of the floxacin family of antibacterial drugs.
A number of pharmaceutical intermediates are also made from Trimethyl Orthoformate.
Trimethyl orthoformate is also an effective reagent for converting compatible carboxylic acids to their corresponding methyl esters. Alternatively, acid-catalyzed esterifications with methanol can be driven closer to completion by employing trimethyl orthoformate to convert water byproduct to methanol and methyl formate.
Intermediate for agrochemicals
Intermediate for pharmaceuticals
Specifications
| Items | Optimal level | Export level |
| Content | ≥99.5% | ≥99.00% |
| Methanol | ≤0.2% | ≤0.3% |
| Methyl Formate | ≤0.2% | ≤0.3% |
| Moisture | ≤0.05% | ≤0.05% |
| Free acid (calculated as formic acid) | ≤0.05% | ≤0.05% |
| Triazine | ≤0.02% | -- |
| Other impurities | ≤0.1 | -- |
Packing specifications
Drums with 200kg weight capacity per drum
Certifications
ISO 9001. ISO 22716. cGMP certified
Kosher, Halal certified
Shipping Information
MOQ: (Due to the nature of chemical transportation, please consult the sea trade manager for details!)
Port of Loading: CHINA - Shanghai Port, Ningbo Zhoushan Port, Guangzhou Port, Qingdao Port, Tianjin Port, Dalian Port, Xiamen Port, Lianyungang Port (can be ensured according to the requirements of customers)
Delivery Time: 4-6 weeks
Payment Terms
L/C, D/P, T/T at buyer’s cost
Sample available on request
Multiple Names
Trimethoxymethane
methoxymethanediol
METHYLFORMIAT-ORTHO
Methyl orthoformate
Trimethylorthoformiat
Trimethyl orthoformate
Thrimethyl orthoformate
Trimethyl ortho formate
orthoformicacidmethylester
TrimethylOrthoFormate(Tmof)
Trimethyl Orthoformate(TMOF)
Orthoformic acid trimethyl ester
- Random Content
- Hot content
- Hot review content
- Flexible Customer and Supplier Relations Specialist (Location: Nigeria)
- Sodium Amyl Xanthate (SAX) 90%, Mining chemical, mining flotation reagent
- Collector BLK-301/Composite Flotating Active Matter ≥60%
- High-strength Shock tube（VOD≧2000m/s）
- Magneto Electric Detonator（Anti stray current）
- Phthalic anhydride
- lithium Carbonates 99.5% Battery Level or 99.2% Industry grade 99%
- 1Discounted Sodium Cyanide (CAS: 143-33-9) for Mining - High Quality & Competitive Pricing
- 2China's New Regulations on Sodium Cyanide Exports and Guidance for International Buyers
- 3Sodium Cyanide 98% CAS 143-33-9 gold dressing agent Essential for Mining and Chemical Industries
- 4International Cyanide（Sodium cyanide） Management Code - Gold Mine Acceptance Standards
- 5China factory Sulfuric Acid 98%
- 6Anhydrous Oxalic acid 99.6% Industrial Grade
- 7Oxalic acid for mining 99.6%
- 1Sodium Cyanide 98% CAS 143-33-9 gold dressing agent Essential for Mining and Chemical Industries
- 2High Quality 99% Purity of Cyanuric chloride ISO 9001:2005 REACH Verified Producer
- 3Zinc chloride ZnCl2 for High Molecular Weight Polymers Initiator
- 4High Purity · Stable Performance · Higher Recovery — sodium cyanide for modern gold leaching
- 5High Quality Sodium Ferrocyanide / Sodium Hexacyanoferr
- 6Gold Ore Dressing Agent Safe Gold Extracting Agent Replace Sodium Cyanide
- 7Sodium Cyanide 98%+ CAS 143-33-9
Online message consultation
Add comment: