Trimethyl Orthoformatepicture1
Trimethyl Orthoformatepicture2

Trimethyl Orthoformate

149-73-5
CAS149-73-5
MFC4H10O3
Technical specifications≥99.00%
  • Levels of danger:3
  • UN NUMBER:3272
  • HS code:29159080
  • MW:106.12
  • Density:0.9±0.1 g/cm3
  • Appearance:Colorless transparent liquid

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Details:

Description

colorless transparent liquid, with odor of ester. Boiling point 103 -105 °C, Relative Density 0.9676(20/4 °C), Refractive index 1.3773 (2.5 °C), Flash point 15 °C, soluble in ethanol and ether and decomposable in water.

Application

Trimethyl orthoformate is a useful building block for creating methoxymethylene groups and heterocyclic ring systems. It introduces a formyl group to a nucleophilic substrate, e.g. RNH2 to form R-NH-CHO, which can undergo further reactions. It is used in the production of some fungicides (for example: azoxystrobin and picoxystrobin), as well as for some members of the floxacin family of antibacterial drugs.

A number of pharmaceutical intermediates are also made from Trimethyl Orthoformate.

Trimethyl orthoformate is also an effective reagent for converting compatible carboxylic acids to their corresponding methyl esters. Alternatively, acid-catalyzed esterifications with methanol can be driven closer to completion by employing trimethyl orthoformate to convert water byproduct to methanol and methyl formate.

  • Intermediate for agrochemicals

  • Intermediate for pharmaceuticals

Specifications

ItemsOptimal levelExport level
Content≥99.5%≥99.00%
Methanol≤0.2%≤0.3%
Methyl Formate≤0.2%≤0.3%
Moisture≤0.05%≤0.05%
Free acid (calculated as formic acid)≤0.05%≤0.05%
Triazine≤0.02%--
Other impurities≤0.1--

Packing specifications

Drums with 200kg weight capacity per drum

Certifications

ISO 9001. ISO 22716. cGMP certified

Kosher, Halal certified

Shipping Information

MOQ: (Due to the nature of chemical transportation, please consult the sea trade manager for details!)

Port of Loading: CHINA - Shanghai Port, Ningbo Zhoushan Port, Guangzhou Port, Qingdao Port, Tianjin Port, Dalian Port, Xiamen Port, Lianyungang Port (can be ensured according to the requirements of customers)

Delivery Time: 4-6 weeks

Payment Terms

L/C, D/P, T/T at buyer’s cost

Sample available on request

Multiple Names

  • Trimethoxymethane

  • methoxymethanediol

  • METHYLFORMIAT-ORTHO

  • Methyl orthoformate

  • Trimethylorthoformiat

  • Trimethyl orthoformate

  • Thrimethyl orthoformate

  • Trimethyl ortho formate

  • orthoformicacidmethylester

  • TrimethylOrthoFormate(Tmof)

  • Trimethyl Orthoformate(TMOF)

  • Orthoformic acid trimethyl ester

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