Description
Clobetasol propionate is a synthetic high-efficiency topical glucocorticoid drug. It has strong anti-inflammatory, anti-pruritic and capillary contraction effects as adrenal corticosteroids and corticotropin drugs. Clobetasol propionate is a synthetic high-efficiency topical glucocorticoid drug. Has strong anti-inflammatory, anti-pruritic and capillary contraction effects.
Application
1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.
2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.
Specifications
Test Items | Specification | Test Results | |
Appearance | White to cream, crystalline powder | White crystalline powder | |
Identification (by IR) | Conforms to CRS spectrum | Conforms | |
Melting point | Approximately 196℃ | 196℃ | |
Specific rotation | +98o - +104o (dried substance) | Conforms | |
Loss on drying | ≤2.0% | 0.1% | |
Residue on ignition | ≤0.10% | 0.05% | |
Heavy metals | ≤20ppm | Conforms | |
Related substances (by HPLC) | Any impurity ≤1.0% Total impurities ≤2.5% | 0.54% 1.22% | |
Assay (by HPLC) | 97.0% ~ 102.0% Calculated on dried basis | 99.5% | |
Type of Packaging
1KG/Bag, 10kg/Carton, 25kg/Drum
Certifications
ISO 9001. ISO 22716. cGMP certified
Kosher, Halal certified
Shipping Information
MOQ: (Due to the nature of chemical transportation, please consult the sea trade manager for details!)
Port of Loading: CHINA - Shanghai Port, Ningbo Zhoushan Port, Guangzhou Port, QinGDAo Port, Tianjin Port, Dalian Port, Xiamen Port, Lianyungang Port (can be ensured according to the requirements of customers)
Delivery Time: 4-6 weeks, depending on order size and destination
Payment Terms
L/C, D/P, T/T at buyer’s cost
Sample available on request
Multiple Names
cgp9555
Dermovate
17-propionate
Cloβsol propionate
CLOBETASOLE PROPIONATE
CLOBETASOL 17-PROPIONATE USP
Clobetasol 17- propionate solution,100ppm
21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1.4-diene-3.20-dione 17-propionate
(11beta,16beta)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3.20-dioxopregna-1.4-dien-17-yl propanoate
(8xi,11beta,14xi,16beta)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3.20-dioxopregna-1.4-dien-17-yl propanoate
[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10.13.16-trimethyl-3-oxo-6.7.8.11.12.14.15.16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
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