High Purity 99% Clobetasol Propionatepicture1
High Purity 99% Clobetasol Propionatepicture2
High Purity 99% Clobetasol Propionatepicture3

High Purity 99% Clobetasol Propionate

(CAS: 25122-46-7)
CAS25122-46-7
MFC25H32ClFO5
Technical specifications≥99.00%
  • Levels of danger:Non dangerous goods
  • UN NUMBER:Non dangerous goods
  • HS code:2937290090
  • MW:466.970
  • Density:1.3±0.1 g/cm3
  • Appearance:White crystalline powder

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Details:

Description

Clobetasol propionate is a synthetic high-efficiency topical glucocorticoid drug. It has strong anti-inflammatory, anti-pruritic and capillary contraction effects as adrenal corticosteroids and corticotropin drugs. Clobetasol propionate is a synthetic high-efficiency topical glucocorticoid drug. Has strong anti-inflammatory, anti-pruritic and capillary contraction effects.

Application

1. Anti-inflammatory effects: The product can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance. Hormone suppression of inflammatory cells, including leukocytes and macrophages accumulation in sites of inflammation and inhibition of phagocytosis, lysosomal enzyme release and synthesis and release of inflammatory chemical mediators. Can reduce and prevent tissue response to inflammation, thereby reducing inflammation performance.

2. Immunosuppressive effect: preventing or inhibiting cell-mediated immune response, delayed hypersensitivity reactions, reducing T lymphocytes, monocytes, eosinophils, reducing immunoglobulin binding to cell surface receptors and inhibition of the synthesis and release of interleukin, thus reducing the T lymphocyte transformation of lymphoblastoid cells, and reduce the extension of the primary immune response. Can reduce immune complexes through the basement membrane, and can reduce the concentration of ingredients complement and immunoglobulins.

Specifications

Test Items

Specification

Test Results

Appearance

White to cream, crystalline powder

White  crystalline powder

Identification (by IR)

Conforms to CRS spectrum

Conforms

Melting point

Approximately 196℃

196℃

Specific rotation

+98o - +104o (dried substance)

Conforms

Loss on drying

≤2.0%

0.1%

Residue on ignition

≤0.10%

0.05%

Heavy metals

≤20ppm

Conforms

Related substances (by HPLC)

Any impurity ≤1.0%

Total impurities ≤2.5%

0.54%

1.22%

Assay (by HPLC)

97.0% ~ 102.0%

Calculated on dried basis

99.5%

Type of Packaging

1KG/Bag, 10kg/Carton, 25kg/Drum

Certifications

ISO 9001. ISO 22716. cGMP certified

Kosher, Halal certified

Shipping Information

MOQ: (Due to the nature of chemical transportation, please consult the sea trade manager for details!)

Port of Loading: CHINA - Shanghai Port, Ningbo Zhoushan Port, Guangzhou Port, Qingdao Port, Tianjin Port, Dalian Port, Xiamen Port, Lianyungang Port (can be ensured according to the requirements of customers)

Delivery Time: 4-6 weeks, depending on order size and destination

Payment Terms

L/C, D/P, T/T at buyer’s cost

Sample available on request

Multiple Names

  • cgp9555

  • Dermovate

  • 17-propionate

  • Cloβsol propionate

  • Clobetasol propionate

  • CLOBETASOLE PROPIONATE

  • CLOBETASOL 17-PROPIONATE USP

  • Clobetasol 17- propionate solution,100ppm

  • 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregna-1.4-diene-3.20-dione 17-propionate

  • (11beta,16beta)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3.20-dioxopregna-1.4-dien-17-yl propanoate

  • (8xi,11beta,14xi,16beta)-21-chloro-9-fluoro-11-hydroxy-16-methyl-3.20-dioxopregna-1.4-dien-17-yl propanoate

  • [(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10.13.16-trimethyl-3-oxo-6.7.8.11.12.14.15.16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate

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